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Grein J, Ohmagari N, Shin D, et al

14 The trial also showed Donanemab slowed cognitive decline by 35% and showed 39% lower risk of progressing to the next stage of the disease when compared to placebo

Given that sarcopenia is a key component of CHE pathophysiology, it is reasonable to test for CHE in patients with reduced muscle mass or muscle strength [44,45,46]