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The potential net public health gain from ENDS substituting for cigarettes is consistent with the tobacco harm reduction principles enunciated by the US Food and Drug Administration (FDA) (US Food and Drug Administration)

Although cigarette smoking has substantially declined since the release of the 1964 Surgeon Generals report on smoking and health,* disparities in tobacco use exist among racial/ethnic populations ( 1 )

Respiratory Health Risks One of the most concerning health effects of using snuffs is the impact on respiratory health

These additional conditions apply: The permit imprint indicia must be located in the upper right corner of the address side of the mailpiece