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The explanation for this discrepancy can be found in recent papers showing that some cancer cell linesincluding HCT116are not affected by L-BSO or GSH synthesis inactivation because they can compensate GSH depletion by the thioredoxin (TXN) pathway 25 , and by maintaining protein homeostasis through deubiquitinating enzymes (DUB) 32

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It is unknown if MHDs impact post-transplant health-related quality of life (HRQOL), a patient-centered outcome important to LT survivors

The 21 healthy participants used either two placebo gums or two gums with 2.5 mg Pycnogenol each, six times daily for 15 min each