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Meanwhile, IPN60090, also known as IACS-6274, has emerged as another promising GLS1 inhibitor, boasting favorable physicochemical properties and pharmacokinetic characteristics, coupled with a remarkable affinity for the target molecule [219, 220]

Under normal circumstances, Kelch-like ECH-associated protein 1 (Keap1) is a negative regulator of Nrf2, which can bind to Nrf2 in the cytoplasm and form a complex with cullin3, and mediates the degradation of Nrf2 ubiquitination

Acupuncture stimulation at GB34 suppresses 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative stress in the striatum of mice

BPC 157-treated rats exhibited normal pupil diameter, microscopically well-preserved ganglion cells and optic nerve presentation, normal fundus presentation, nor- mal retinal and choroidal blood vessel presentation, and normal optic nerve presentation

However, L-carnitine plays a positive role in the neurodevelopment of preterm infants