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[DOI] [PubMed] [Google Scholar] Schubert M, Gautam D, Surjo D, Ueki K, Baudler S, Schubert D, Kondo T, Alber J, Galldiks N, Kustermann E, Arndt S, Jacobs AH, Krone W, Kahn CR, Bruning JC, 2004

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Results Confocal imaging reveals morphological alterations in AC16 cells following DOX exposure To study mitochondria-related cardiac toxicity, we first performed functional and morphological analyses of confocal images of the cardiac AC16 cell line treated with various types of mitochondrial inhibitors, including DOX (Fig

Furthermore, both high and low doses of acrolein, as well as prolonged exposure to acrolein, result in cellular damage through immunological and inflammatory mechanisms