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(4) metabolic inhibitors + autophagy inhibitors to prevent adaptive responses

For example, red blood cells are elastic, which means they can be distorted but bounce back to their original shape

They then used single-cell sequencing of the TCRs of these clonally expanded CD8+ T-cells and expressed them as recombinant TCRs to screen for potential HLA-B*27:05-restricted peptides that engage these disease-associated TCRs and were able to narrow down the millions of possibilities to a very short list of human and microbial proteins

Merchant, A

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