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TABLE 2 Characteristics of the included studies

CD38_targeting monoclonal antibodies (mAbs), including daratumumab (DARA) and isatuximab (ISA), exert antitumor activity through direct cytotoxicity and immune modulation

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To test this hypothesis, we first validated the RNA-seq results by RT-qPCR experiments: cytosolic RPGs ( RPS6A / RPS6B , RPS22A , RPL38 , RPL31A ), as well as a mitochondrial RPG ( MRPL50 ), were significantly downregulated in the context of V-ATPase-dependent autophagy ( Fig

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