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doi: 10.1111/j.1469-7580.2012.01551.x

Generally between 30-60 minutes

Rapid injection can cause discomfort and may affect peptide distribution

Lassoued S, Ben Ameur R, Ayadi W, Gargouri B, Ben Mansour R et al

Third, hyperhomocysteinemia detected both under basal conditions and after a methionine challenge (approximately 50% of patients), which might be partially explained by a saturation of the transsulfuration pathway caused by dietary methionine excess