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1C), suggesting that tumor mitochondria are in greater need of antioxidative protection

10.1111/j.1600-0625.2010.01144.x 33 LeeH.HongY.KimM

Additionally, ATF3 regulates genes such as acyl-CoA synthetase long chain family member 4 and lipoxygenases, essential for producing and incorporating PUFAs into cellular membranes, which is a critical step in lipid peroxidation (119121)