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1 Introduction Numerous scientific studies have confirmed the role of diet in maintaining the proper functioning of the human body and in the prevention and treatment of various diseases, including obesity, diabetes, and cardiovascular disease ( 2 History of the ketogenic diet The earliest reports on the use of a low-carbohydrate diet to reduce the severity of symptoms, especially epileptic seizures, date back to antiquity ( In 1911, French doctors Guelpe and Marie published the first scientific report on the benefits of intermittent fasting in epilepsy ( In 1925, Dr

Screening for hemochromatosis: patients with liver disease, families, and populations

However, its clinical application has been limited by dose-dependent gastrointestinal toxicity observed in later phase I and II clinical trials

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Inflammatory conditions in the airway epithelial cells upregulate NOX-4, and the ROS generated by NOX-4 react with NO to produce peroxynitrite, thereby lowering the availability of NO for bronchodilation (94, 97)