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Glutamine addiction extends from the context of MYC, and mutations in KRAS a key gene related to the stability and activity of c-MYC protein in cancer cells similarly cause dependence on exogenous glutamine for cellular growth and proliferation, as does MYC amplification (162, 179, 180)

Jiang YJ, Ho TL,Chao CC,He XY

falciparum glutathione redox system comprises the electron donor NADPH, a highly active PfGR located in the cytosol and the apicoplast, and reduced/oxidized glutathione (GSH/GSSG) [21], [22], [23]

Recently endosomal processing has been demonstrated to play a pivotal role in the progression of HCC (Hu et al., 2015)