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For instance, the number of genes upregulated with age is markedly higher in muscle, lung, and blood than in the brain or the kidney

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Adopting a holistic lifestyle that includes a healthy diet, improved indoor air quality, and stress management further enhances the bodys resilience against these environmental toxins

It is believed that early stages of frailty are amenable to interventions that could avert adverse outcomes, including the increased risk of hospitalization and premature death (116)

Microglial complement receptor 3 can induce ferroptosis via NADPH oxidase 2 (NOX2) (60), and other NADPH oxidases, including NOX1 (61) and NOX4 (62), are also key contributors to the ferroptotic process