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Nature 556 , 332338 (2018)

J Rheumatol (2016) 43(7):12634

Eventually, when enough thyroid tissue is attacked, the body no longer produces thyroid hormone

It is noteworthy that Pt-induced ROS production impairs antioxidant enzymes [e.g., superoxide dismutase (SOD) and catalase (CAT)] to trigger oxidative stress (Khasabova et al., 2019), which participates in the onset and progression of both acute and chronic PIPN

Primary cultures also offer the versatility of adapting differentiation protocols to allow a mixed culture of neurons and glial cells, such as microglia, more closely capturing the influence of immune system modulation in PD pathology [108, 109]