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Both peptides exhibit the potential to modulate an immune response to attenuate certain conditions, as a result of which administering BPC-157 and TB-500 together may provide even stronger effects [10, 19, 20]

The obtained tissue explants were cultured in DMEM/F-12 (Gibco, USA) supplemented with 10% fetal bovine serum (FBS, Gibco, USA) and 2% penicillin/streptomycin (Sigma, Germany) and incubated at 37 C and 5% CO 2 until the outgrowing cell confluence reached 80%

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In parallel, we exposed our U937 cell lines to TNF- , expecting similar protection, as Fas is a member of the tumour necvosis factor (TNF) receptor superfamily (Itoh et al, 1991

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