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In addition, by analysis of DNA replication intermediates using electron microscopy, we found that RNase H1 overexpression completely suppressed replication fork reversal induced by HRASV12 or cyclin E1 overexpression in U2OS T-REx [RNH1-GFP] (Fig

The results showed that the concentration of uricase reached 5 U/mL, and the cell viability decreased to only 64.1%, indicating that the H 2 O 2 generated through the degradation of UA by uricase could effectively induce cell death (Fig

Growth phenotypes of reductase mutants Previous studies have examined the growth kinetics of glr1 (Grant et al ., 1996a) and trr1 (Trotter & Grant, 2002) mutant strains

Peng C, Xue L, Yue Y, Chen W, Wang W, Shen J (2023) Duloxetine HCl alleviates asthma symptoms by regulating PI3K/AKT/mTOR and Nrf2/HO-1 signaling pathways

Inside-out signaling subsequently trigger outside-in signaling, which induces spreading and clot retraction contributing to thrombus formation [55]