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Addition of sodium kenodeoxycholate and propyl gallate did not change the solubility profile of the MEDI7219 (SEQ ID NO: 2) peptide, maintained in the range of pH 7.0 to pH 9.0

Taken together, our data indicates a significant role for glutathione, not only in oxidative protein folding of periplasmic proteins, but also by balancing and maintaining the periplasmic redox homeostasis

Additionally, chondrocyte death is difficult to repair, and a degree of mitochondrial autophagy is necessary for chondrocyte protection when stress occurs (243)