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Biothiols, Part A: Monothiols and Dithiols, Protein Thiols, and Thiyl Radicals

When RHIM2 ZBP1 is occupied, the free RHIM1 ZBP1 domain can recruit RIPK1 and/or RIPK3, eventually leading to the recruitment of effector molecules, completing the assembly of the PANoptosome and driving PANoptosis [74]

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FFA promotes nuclear factor-B-dependent TNF- expression by mediating lysosomal instability and stimulating increased hepatotoxicity to impair normal hepatic metabolic function [35]