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Description

C3a and C5a receptor antagonists ameliorate endothelial-myofibroblast transition via the Wnt/-catenin signaling pathway in diabetic kidney disease

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Required for mitochondrial function and ATP (energy) production

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Incipient oxidative stress is associated with increased hippocampal protein levels of TOP2 and expression of early response genes (ERGs) While excessive ROS is associated with decreased performance in cognitive function, physiological concentrations of ROS are necessary to regulate activity-dependent neuronal plasticity 67

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