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Long-Term Mortality Risk: Cigarette smoking is lethal due to: Cancer risk Progressive COPD Cardiovascular mortality Acute Lung Injury Risk: Vaping carries: Risk of sudden severe lung injury Unpredictable inflammatory response Unknown long-term carcinogenic potential The Key Concern: Vaping has not existed long enough for us to fully understand its long-term consequences

This biopsy-based approach -- using sophisticated single-cell analyses in collaboration with Sandeep Datta, M.D., Ph.D., at Harvard University -- revealed widespread infiltration of T-cells engaged in an inflammatory response in the olfactory epithelium, the tissue in the nose where smell nerve cells are located

Floored, floored. Jim was obsessed with what he called the unvarnished truth. He hated the fake, plastic world of the 1950s that the Beat Generation blew up