can l-carnitine cause liver damage Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation | Journal of Translational Medicine Effect of L-Carnitine Supplementation on

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For instance, high expression of HIF-1 has been associated with unfavorable responses to treatment in hepatocellular carcinoma undergoing local ablation therapies, as well as in oral cancer and locally advanced head and neck squamous cell carcinomas treated with cisplatin and radiation therapy [236238]

Acknowledgements We thank Prof Wangsen Cao for their critical review and thoughtful discussion of the manuscript

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The mechanism involves complementary pathways