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This result is consistent with data from a single-cell sequencing study which specifically profiled cells isolated from the adult mouse cerebellum [28]

Funding This work was supported by a Medical Research Council award (COEN-Centres of Excellence for Neurodegeneration MRC/S004920/1) to PJS, RJM and MC and by the MND Association AMBRoSIA (A multi-centre biomarker resource resources strategy for ALS) programme (Oct15/972797) to PJS, MRT and AM

On the other hand, inhibition of GSH synthesis with BSO, independently of the cysteine pool, has been repeatedly described to induce ferroptosis ( via depletion of mitochondrial GSH pool leading to the release of cytochrome c, when combined with chemotherapy in breast cancer and leukemia, respectively (71, 72)

Keep stimulation low screens, noise, and bright light all make headache and anxiety worse