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Previous studies further indicate that inhibiting IL-6 signaling significantly reduces neutrophil migration and infiltration, thereby mitigating local inflammation 28,29 , consistent with evidence that blocking IL-6 activity modulates innate immune cell recruitment and provides therapeutic targets for neuroinflammatory conditions 30

In Parkinsons disease (PD) models, exercise increases the density of dendritic spines in medium spiny neurons (MSNs) in the striatum, thereby improving motor dysfunction (Palasz et al., 2019)

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