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Increasing both levels of ROS and reactive nitrogen species (RNS) through the destruction of cellular structures, such as DNA, proteins, and lipids, can increase the risk of migraine

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Experimental research suggests potential effects in tissue repair, inflammation control, and regenerative signaling, but clinical evidence remains limited

The pipeline for performing this analysis is previously described (Levitin et al, 2019) and the corresponding code can be found at We defined the transformed glioma cells as cells in clusters that exhibit statistical enrichment of the Cre recombinase transcript