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[2] That work reported a long half-life on the order of 159195 hours (about 78 days) consistent with once-weekly dosing, and it provided the first human safety and tolerability read on the cagrilintide-plus-incretin concept that later became CagriSema

Doctors swear an oath to first, do no harm, and are expected to use treatments supported by evidence or, at minimum, a plausible expectation of benefit outweighing risks

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The compound reduces pro-inflammatory cytokines (TNF-alpha and IL-6), limiting excessive tissue damage that prolongs recovery