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Funding This work was supported by the National Science and Technology Major Project (2022ZD0117700), the National Natural Science Foundation of China (32270759) and the Research Foundation for Postdoctoral (AUGA5710026124)

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

After 48 h, the mice were sacrificed, and the tumors as well as major organs (heart, liver, spleen, lung, kidney) were collected to measure their fluorescence intensity

Argatroban and Reproterol, both FDA-approved for other indications, enhance lipolysis and reduce lipid accumulation, and are currently under investigation for NASH treatment [419, 420]