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However, in clinical applications, targeted therapies often exhibit multi-target effects, which can lead to both toxic side effects on normal cells and enhanced tumor cell cytotoxicity [37]

10.1073/pnas.2221116120 [DOI] [PMC free article] [PubMed] [Google Scholar] Pencik J., Philippe C., Schlederer M., Atas E., Pecoraro M., Grund-Grschke S., et al

The glutathione disulfide (GSSG) formed can be recycled to GSH by glutathione reductase in the presence of NADPH

These include mild redness, light swelling, occasional bruising, and a temporary burning or cramping sensation at the injection point

Meanwhile, ATF4 is linked two relatively independent events of autophagy with ferroptosis in HuOCSCs