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Of these seven groups, the Firmicutes , Proteobacteria , and Verrucomicrobia phyla demonstrated a significant main effect of treatment group on relative abundance after BenjaminiHochberg correction for multiple comparisons, while Bacteroidetes and Actinobacteria demonstrated significant main effects of treatment group on relative abundance before BenjaminiHochberg correction

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Transient receptor potential vanilloid-1 signaling inhibits differentiation and activation of human dendritic cells

The peptide does not bind to a known receptor with high specificity, which complicates mechanistic classification

The TLR4-NF-B pathway is also inhibited by SSB2 in LPS-induced microglia, which suppresses the activation of microglia and reduces the levels of IL-1, IL-6, and TNF-, increasing the anti-inflammatory cytokine IL-10 (Wang et al., 2023)