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Vaccination strategies have gained prominence, with strong recommendations for the administration of inactivated vaccines, including influenza, pneumococcal, and COVID-19 vaccines, to all patients with CLL, ideally prior to treatment initiation

Lentivirus was generated by transfecting HEK293T cells plated to roughly 60% confluency in a six-well dish with 250 ng of pMD2.G, 750 ng of psPAX2 and 1,000 ng of lentiviral vector containing the gene of interest with 10 l of PEI in serum-free medium

Some may experience minor side effects such as: Redness or swelling at the injection site Temporary soreness or bruising Less commonly, side effects could include: Mild headaches Nausea Itchy skin or rash Should you notice any prolonged side effects, we recommend speaking with your GP or calling NHS 111 for advice