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While these adaptations are protective in the short term, repeated or prolonged activation can cause cumulative strain across multiple systems

Atezolizumab and nab-paclitaxel in advanced triple-negative breast cancer

Endoplasmic reticulum stress/Ca(2+)-calmodulin-dependent protein kinase/signal transducer and activator of transcription 3 pathway plays a role in the regulation of cellular zinc deficiency in myocardial ischemia/reperfusion injury

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developed a cerium oxide nanoparticlemicroRNA-146a complex (CNP-miR146a) that simultaneously attenuates oxidative stress and modulates inflammation via the NF-B signaling pathway