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While these provide valuable mechanistic insights, additional in vivo studies are required to confirm the effects of FM19G11-loaded NPs on epSPC energy metabolism and, crucially, to demonstrate their capacity to promote neurogenesis

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Talanta 165 , 346350 (2017)

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By targeting the Nrf2 signaling pathway with compounds, such as osthole, 5-hydroxymethyl-2-furfural (5-HMF), and paeonol, researchers have effectively reduced oxidative damage and BBB permeability in mouse models of ischemia (Zhao et al., 2014

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