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London, Appleton & Lange, p 797

Both of the double blinded randomised intervention trials provided information about concealment and the laboratory was blinded thereby reducing performance and detection bias [64, 65]

For example, NMN has research to support its ability to improve skin health and enhance aerobic capacity, which NR doesnt.37 4 Meanwhile, NR has research that shows it can improve biomarkers associated with neurodegenerative disease, which cant be said of NMN.30 If you wanted to boost NAD+ levels, improve aerobic capacity, and protect your brain with a single supplement, a combination of NMN and NR may be superior to either in isolation

they are biomimetic delivery systems

Thus, targeting of the transporters expressed only at the BBB would be useful in terms of delivery of drugs with extracellular targets in the brain, while utilization of the transporters expressed at the BBB and cellular membrane of the brain parenchymal cells is essential for delivery of the drugs with intracellular targets