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Commercial sweeteners are widely used in processed foods like soft drinks, candy, chewing gum, and cereal, and are frequently co-formulated with other sweeteners, the flavor compound vanillin, and the neurostimulator caffeine

Although evidence of manganeses function in the immune response is somewhat limited, it serves as a structural component in the Mn-SOD enzyme, also crucial in neutralizing ROS produced by phagocytic cells (Figure 1)

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Ginsenoside Rg1 ameliorates neuroinflammation via suppression of Connexin43 ubiquitination to attenuate depression