Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether CA-amide-PEG4-Biotin is a Biotin-HaloTag ligand

CA-amide-PEG4-Biotin is a Biotin-HaloTag ligand that enables rapid labeling of Halo-tagged proteins and their efficient isolation via streptavidin pull-down

2341796-77-6 (2HCl salt) Molecular Formula C29H45Cl2N5O4S Molecular Weight 630

1039/D4CB00184B

Product Name: Lissamine rhodamine B PEG3 alkyne Synonyms: Sulforhodamine B PEG3 alkyne CAS Number: N/A Molecular Formula: C36H45N3O9S2 Molecular Weight: 727

S)-AHPC-acetamido-O-PEG4-C1-acid Synonyms CAS Number 2172820-13-0 Related CAS Molecular Formula C34H50N4O11S Molecular Weight 722

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether CA-amide-PEG4-Biotin is a Biotin-HaloTag ligandSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I