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In Atg7-deficient mice, the loss of autophagy in hematopoietic stem cells not only leads to increased aberrant myeloid expansion, resulting in severe myeloid dysplasia and infiltrating myeloid blast cells evoking AML [18] but can also activate the NOTCH signaling pathway, blocking HSC differentiation and leading to a leukemic phenotype [19]

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B., Lyles, G

Farrell was appointed General Counsel in 2010 with the additional role of University Secretary in 2015

And there are even surgical procedures to help trim the prostate in ways that allow you to urinate more easily