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Furthermore, in a novel AlbuMus RAG1 knockout model (AlbuMus RAG1 KO) bearing EGFR-positive BRAF mutated tumours, we demonstrate superior anti-tumour effects after a single dose of the Albu-LiTE construct compared to a conventional Fc-less LiTE format and a full-length anti-EGFR monoclonal antibody

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Researchers study NNMT and its inhibitors in the context of nicotinamide handling, methyl donor utilization, and metabolic regulation across different model systems

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