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Patients were categorized into high-risk and low-risk groups according to the signature, with the high-risk group showing significantly worse overall survival (5-year survival: 38.9% compared to 79.8% in the low-risk group)

Patients on chemotherapy (cisplatin, cyclophosphamide may interact)

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The role of the UPS in metabolic diseases Dysfunction of the UPS has emerged as a key factor in the development of metabolic disorders, including obesity, T2DM, and MASLD

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