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Aside from yielding mixed results, diets may be difficult to implement due to higher costs, food access challenges, cultural dietary preferences, and compliance issues further compounded by modern lifestyle factors such as time constraints and irregular schedules (94)

By selectively disrupting IGF- 1R in endothelial cells, we observed microvascular rarefaction, impaired functional hyperemia, and reduced muscle endurance, all occurring independently of muscle mass loss

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The potential utility of tight junction regulation in celiac disease: focus on larazotide acetate