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In G2, CyclinA-CDK2-phosphorylated BORA acts a potent activator of Aurora-A and the resulting BORA:Aurora-A complex is vital for PLK1 activation and mitotic entry (Seki et al, 2008b

Familial PS mutations conferring loss of an essential or trophic function, such as ferroptosis suppression, is consistent with prior findings

The BSO-induced increased in glutamate shape excitatory transmission

PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 50 H 69 N 15 O 9 Weight: 1024.20 g/mol CAS: 121062-08-6 Structure: Cyclic heptapeptide with lactam bridge PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Soluble in water and acetic acid Selectivity: Non-selective MC1R/3R/4R/5R agonist Storage: Keep refrigerated 3646 F (28 C) Related products DSIP $55.00 $90.00Price range: $55.00 through $90.00 MOTS-c $60.00 $190.00Price range: $60.00 through $190.00