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In 2024 alone, it surpassed lung cancer as the most diagnosed cancer type worldwide, with over 2.3 million new cases every year (27)

However, selenium deficiency significantly reduces GPx activity, with studies reporting a 3050% drop in enzymatic function, particularly in critically ill patients [67,68,69]

Potential CNS Access : Some research suggests nasal administration may facilitate direct transport to the central nervous system via olfactory and trigeminal nerve pathways, though this remains an area of ongoing investigation [5]