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At a dose of 0.5 mg/kg, Dihexa completely reversed scopolamine-induced cognitive deficits in rat models

Fibronectin, vimentin, and alpha-smooth muscle actin (-SMA) are three important ECM proteins that play key roles in the pathogenesis of pulmonary fibrosis

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By contrast, in cardiomyocytes from Tfam homozygous knockout mice, which undergo mtDNA depletion associated with severe RC dysfunction, the initial increased ROS production is neutralized by induction of the antioxidant defences, as illustrated by the measurement of GPx and aconitase enzyme activities 51