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MR-PRESSO detected outliers in the overall associations with CAD in FinnGen (shown in Additional file 1: Table S5), where we used corrected estimates from MR-PRESSO

Resolution of symptoms did not correlate with duration or severity of the disorder at presentation or with any of the other variables analyzed (sex, age at diagnosis, admission to the hospital, identification of trigger factors, travel sickness, family history of migraine) (29)

Inhibition of PPAR leads to serum acylcarnitine accumulation [190], whereas hepatic PPAR activation induced by energy deprivation or fibrates is associated with an increase in the carnitine concentration and a decrease in serum acylcarnitine accumulation [191, 192]

However, there was no difference in Frailty Index and hand grip test scores between supplemental L-carnitine and placebo groups