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Gene mutations can lead to alterations in normal cellular activity, contribute to increased oxidative stress, cause mitochondrial dysfunction, and increase the rate of cell death

Additionally, the study utilized Passing-Bablok similarity analysis to further compare the modified GPx-DTNB method with the original GPx Assay (Rotruck et al

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Clinical conditions associated with glutathione depletion include increased oxidative stress and dysfunction of enzymes within the -glutamyl cycle

Tools Quant II Fast RT kit (Biotools, Jupiter, FL, USA) was used to perform reverse transcription of the cDNA