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Monotherapy and combination therapy using anti-angiogenic nanoagents to fight cancer

doi: 10.1111/j.1471-4159.2009.06404.x 69 IdelmanG.SmithD

doi:10.1155/2019/1528635

The catalytic efficiency of HsaGST A3-3 with 5-AD is 5000-fold higher than that of HsaGST A2-2, and we found that mutating the five residues in the H-site of HsaGST A2-2 into the corresponding HsaGST A3-3 residues enhanced the efficiency to 70% of the HsaGST A3-3 value (Pettersson et al., 2002)