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Owing to its high incidence, AV affects approximately 95% of teenage boys and 85% of adolescent girls, and almost 50% of individuals continue to experience AV into adulthood 1,4

This defense lowers the possibility of harm to lipids, proteins, and DNA while also assisting in the preservation of cellular integrity (1)

In contrast to the adaptability of normal tissues, this metabolic inflexibility in cancer cells provides a biochemical basis for selective PLP pathway inhibition