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While preclinical data suggest that prodromal-stage modulation of the NTF-mitochondria axis may reduce neuronal loss, translating this finding to humans requires reliable biomarkers (e.g., cerebrospinal fluid -synuclein oligomers, mitochondrial DNA mutation burden) and imaging tools (e.g., dopamine transporter PET) for precise disease staging

The multiple actions of grape and its polyphenols on female reproductive processes with an emphasis on cell signalling