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The serine de novo synthesis pathway (SSP) represents a pivotal metabolic bypass of glycolytic metabolism, whereby the glycolytic intermediate 3-phosphoglyceric acid is converted into serine and glycine through the action of numerous metabolic enzymes, including phosphoglycerate dehydrogenase (PHGDH)

The CDO products sulphite and CSA are toxic to lung cancer cells

MiRNA is a small noncoding RNA molecule, 2122 nucleotides long, that promotes mRNA degradation by inhibiting translation or binding semi-complementarily to the 3 untranslated region (UTR), thereby regulating post-transcriptional gene expression 109,110

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