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Joshua Mansour, a Los Angeles-based oncologist, told Drugwatch

They were randomly split into four groups: half took the medication bupropion while the other half took placebo pills, and half of each medication group also received either the Positively Smoke Free program or just a brief quit smoking advice session

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Because many reports suggest that CKD patients die before ESRD onset, 16, 17 especially among older patients, 18 this study might have underestimated the effect of smoking on CKD because ESRD was the study outcome