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Yes, researchers have explored intranasal administration in some studies, but absorption can be variable and is less standardized than subcutaneous injection

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[3][4] Researchers suggest that MC-4R agonism, potentially combined with existing modalities, may encourage both physiological and psychological alterations

Combining PT-141 with PDE5 inhibitors may increase the risk of priapism, a prolonged and painful erection that requires immediate medical attention

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