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Glutathione deficiency increases oxidative stress

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demonstrated that iron chaperones PCBP1/2 mediate iron dysregulation, linking GSH depletion to ferroptosis [60]

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When this increase is measured as a percentage compared to a placebo (with a baseline of 1.31mIU/l or 0.4ng/ml), the enhancement appeared to have exceeded a 60-fold uplift

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