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BACH1 expression is also markedly upregulated in the ventral midbrains (VBMs, the brain region containing SNPC) of mice treated with MPTP

We also observed increased Bone Morphogenetic Protein 6 ( BMP6 ) expression in KO PFG 34,35 , suggesting a pro-liver-like bias in GPX2 KO foregut endoderm

While the changes to RBCs resulting from hypothermic storage-induced biochemical and structural alterations (i.e

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Repeat-dose toxicology studies were conducted in rats and dogs, up to 13-weeks in duration, and clinical pathology endpoints including thyroid hormones were assessed at 2-, 6-, and 13-weeks, as well as following 2- to 4-weeks of recovery